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The 3D structures of the homologous Mn and Fe superoxide dismutases have the same arrangement of alpha-helices, and their active sites contain the same type and arrangement of amino acid side-chains

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(2000) 71:1256S61S

Research with genetically transformed mice would provide the most useful information, but they are expensive and time consuming to work with

This occurs through oxidation, reduction and hydrolysis of substances via cytochrome P450 enzymes

Targeted sequencing identified FBXW7 mutations in 15 of these tumors, yielding a mutation frequency consistent with previous EC studies [5]